HTML5 Boilerplate

HTML5 Boilerplate is the professional badass's base HTML/CSS/JS template for a fast, robust and future-proof site.
After more than two years in iterative development, you get the best of the best practices baked in: cross-browser normalization, performance optimizations, even optional features like cross-domain ajax and flash. A starter apache .htaccess config file hooks you the eff up with caching rules and preps your site to serve HTML5 video, use @font-face, and get your gzip zipple on.
Boilerplate is not a framework, nor does it prescribe any philosophy of development, it's just got some tricks to get your project off the ground quickly and right-footed.

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摘自:http://html5boilerplate.com/